Directions for the Student:
There are 4 essay questions. Please be sure to complete all of them with thorough substantive responses. Citations are required for all responses. There is no time limit;
Questions
Construct a paragraph describing the interrelationship among the microbial pathogen, the affected host, and potential antimicrobial drugs in the development of an appropriate chemotherapeutic treatment.
A critically ill patient enters your emergency room, exhibiting signs and symptoms of severe septic shock. In this case, should you immediately begin treatment with a broad-spectrum drug or a narrow-spectrum drug? Explain your answer and discuss any possible consequences of using either drug in the patient.
Amphotericin B is often referred to as “Amphi-Terrible” in medical settings due to its effects in treated patients. Describe when this drug should be prescribed, and provide a biological reason for its damaging activity on host cells. HAART, or highly active antrireoviral therapy, is currently recommended for the treatment of HIV and involves the administration of three or more medicines at one time. Explain why this combined therapy approach is more effective than single drug treatment in the management of HIV infection, providing current evidence to support your answer.
Antibiotic-resistance genes, as well as other virulence factor genes, are especially passed between bacterial cells through horizontal gene transfer. Conduct additional research on New Delhi metallo-beta-lactamase 1 strains of bacteria, and explain why medical tourism poses a serious threat to the spread of this organism. Provide evidence to support your explanation.
Answer
Question 1
Bacteria need hosts to live in so they can obtain food and nourishment. Although some forms of bacteria are beneficial to the body of the host since they enhance digestion and other important actions, most are harmful since they trigger diseases. Potential antimicrobial drugs can either be broad-spectrum or narrow-spectrum (Tortora, Funke, & Case, 2018). Each drug option has a minimum… To access full answer (100% correct), click on the purchase button below to proceed.